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Epigenetic regulation of macrophage polarization and inflammation by DNA methylation in obesity
Obesity is associated with increased classically activated M1 adipose tissue macrophages (ATMs) and decreased alternatively activated M2 ATMs, both of which contribute to obesity-induced inflammation and insulin resistance. However, the underlying mechanism remains unclear. We find that inhibiting D...
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| Udgivet i: | JCI Insight |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Clinical Investigation
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5111504/ https://ncbi.nlm.nih.gov/pubmed/27882346 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.87748 |
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