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Epigenetic regulation of macrophage polarization and inflammation by DNA methylation in obesity

Obesity is associated with increased classically activated M1 adipose tissue macrophages (ATMs) and decreased alternatively activated M2 ATMs, both of which contribute to obesity-induced inflammation and insulin resistance. However, the underlying mechanism remains unclear. We find that inhibiting D...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:JCI Insight
Main Authors: Wang, Xianfeng, Cao, Qiang, Yu, Liqing, Shi, Huidong, Xue, Bingzhong, Shi, Hang
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Clinical Investigation 2016
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5111504/
https://ncbi.nlm.nih.gov/pubmed/27882346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.87748
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