Epigenetic regulation of macrophage polarization and inflammation by DNA methylation in obesity

Obesity is associated with increased classically activated M1 adipose tissue macrophages (ATMs) and decreased alternatively activated M2 ATMs, both of which contribute to obesity-induced inflammation and insulin resistance. However, the underlying mechanism remains unclear. We find that inhibiting D...

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Detaylı Bibliyografya
Yayımlandı:JCI Insight
Asıl Yazarlar: Wang, Xianfeng, Cao, Qiang, Yu, Liqing, Shi, Huidong, Xue, Bingzhong, Shi, Hang
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2016
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5111504/
https://ncbi.nlm.nih.gov/pubmed/27882346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.87748
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