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Omega-3 Polyunsaturated Fatty Acids Antagonize Macrophage Inflammation via Activation of AMPK/SIRT1 Pathway

Macrophages play a key role in obesity-induced inflammation. Omega-3 polyunsaturated fatty acids (ω-3 PUFAs) eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) exert anti-inflammatory functions in both humans and animal models, but the exact cellular signals mediating the beneficial effects...

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Detalhes bibliográficos
Main Authors: Xue, Bingzhong, Yang, Zhenggang, Wang, Xianfeng, Shi, Hang
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3465287/
https://ncbi.nlm.nih.gov/pubmed/23071533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045990
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