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Macrophage α1 AMP-activated Protein Kinase (α1AMPK) Antagonizes Fatty Acid-induced Inflammation through SIRT1

In this study, we aim to determine cellular mechanisms linking nutrient metabolism to the regulation of inflammation and insulin resistance. The nutrient sensors AMP-activated protein kinase (AMPK) and SIRT1 show striking similarities in nutrient sensing and regulation of metabolic pathways. We find...

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Detalhes bibliográficos
Main Authors: Yang, Zhenggang, Kahn, Barbara B., Shi, Hang, Xue, Bing-zhong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885183/
https://ncbi.nlm.nih.gov/pubmed/20421294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.123620
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