Inhibiting DNA Methylation by 5-Aza-2′-deoxycytidine Ameliorates Atherosclerosis Through Suppressing Macrophage Inflammation

Inflammation marks all stages of atherogenesis. DNA hypermethylation in the whole genome or specific genes is associated with inflammation and cardiovascular diseases. Therefore, we aimed to study whether inhibiting DNA methylation by DNA methyltransferase inhibitor 5-aza-2′-deoxycytidine (5-aza-dC)...

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Bibliografische gegevens
Gepubliceerd in:Endocrinology
Hoofdauteurs: Cao, Qiang, Wang, Xianfeng, Jia, Lin, Mondal, Ashis K., Diallo, Abdoulaye, Hawkins, Gregory A., Das, Swapan K., Parks, John S., Yu, Liqing, Shi, Huidong, Shi, Hang, Xue, Bingzhong
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Endocrine Society 2014
Onderwerpen:
Renal-Cardiac-Vascular
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4239421/
https://ncbi.nlm.nih.gov/pubmed/25251587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2014-1595
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