Inhibiting DNA Methylation by 5-Aza-2′-deoxycytidine Ameliorates Atherosclerosis Through Suppressing Macrophage Inflammation

Inflammation marks all stages of atherogenesis. DNA hypermethylation in the whole genome or specific genes is associated with inflammation and cardiovascular diseases. Therefore, we aimed to study whether inhibiting DNA methylation by DNA methyltransferase inhibitor 5-aza-2′-deoxycytidine (5-aza-dC)...

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Detalles Bibliográficos
Publicado en:Endocrinology
Autores principales: Cao, Qiang, Wang, Xianfeng, Jia, Lin, Mondal, Ashis K., Diallo, Abdoulaye, Hawkins, Gregory A., Das, Swapan K., Parks, John S., Yu, Liqing, Shi, Huidong, Shi, Hang, Xue, Bingzhong
Formato: Artigo
Lenguaje:Inglês
Publicado: Endocrine Society 2014
Materias:
Renal-Cardiac-Vascular
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4239421/
https://ncbi.nlm.nih.gov/pubmed/25251587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2014-1595
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