Inhibiting DNA Methylation by 5-Aza-2′-deoxycytidine Ameliorates Atherosclerosis Through Suppressing Macrophage Inflammation

Inflammation marks all stages of atherogenesis. DNA hypermethylation in the whole genome or specific genes is associated with inflammation and cardiovascular diseases. Therefore, we aimed to study whether inhibiting DNA methylation by DNA methyltransferase inhibitor 5-aza-2′-deoxycytidine (5-aza-dC)...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Endocrinology
मुख्य लेखकों: Cao, Qiang, Wang, Xianfeng, Jia, Lin, Mondal, Ashis K., Diallo, Abdoulaye, Hawkins, Gregory A., Das, Swapan K., Parks, John S., Yu, Liqing, Shi, Huidong, Shi, Hang, Xue, Bingzhong
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Endocrine Society 2014
विषय:
Renal-Cardiac-Vascular
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4239421/
https://ncbi.nlm.nih.gov/pubmed/25251587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2014-1595
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