Inhibiting DNA Methylation by 5-Aza-2′-deoxycytidine Ameliorates Atherosclerosis Through Suppressing Macrophage Inflammation

Inflammation marks all stages of atherogenesis. DNA hypermethylation in the whole genome or specific genes is associated with inflammation and cardiovascular diseases. Therefore, we aimed to study whether inhibiting DNA methylation by DNA methyltransferase inhibitor 5-aza-2′-deoxycytidine (5-aza-dC)...

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Detalles Bibliográficos
Publicado en:Endocrinology
Main Authors: Cao, Qiang, Wang, Xianfeng, Jia, Lin, Mondal, Ashis K., Diallo, Abdoulaye, Hawkins, Gregory A., Das, Swapan K., Parks, John S., Yu, Liqing, Shi, Huidong, Shi, Hang, Xue, Bingzhong
Formato: Artigo
Idioma:Inglês
Publicado: Endocrine Society 2014
Assuntos:
Renal-Cardiac-Vascular
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4239421/
https://ncbi.nlm.nih.gov/pubmed/25251587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2014-1595
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