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Cullin-3 mutation causes arterial stiffness and hypertension through a vascular smooth muscle mechanism
Cullin-3 (CUL3) mutations (CUL3Δ9) were previously identified in hypertensive patients with pseudohypoaldosteronism type-II (PHAII), but the mechanism causing hypertension and whether this is driven by renal tubular or extratubular mechanisms remains unknown. We report that selective expression of C...
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| Publicado no: | JCI Insight |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5111503/ https://ncbi.nlm.nih.gov/pubmed/27882355 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.91015 |
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