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Identification of Transcribed Enhancers by Genome-wide Chromatin Immunoprecipitation Sequencing

Recent work has shown that RNA polymerase II mediated transcription at distal cis-regulatory elements serves as a mark of highly active enhancers. Production of non-coding RNAs at enhancers, termed eRNAs, correlates with higher expression of genes that the enhancer interacts with; hence eRNAs provid...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Methods Mol Biol
Hauptverfasser: Blinka, Steven, Reimer, Michael H., Pulakanti, Kirthi, Pinello, Luca, Yuan, Guo-Cheng, Rao, Sridhar
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5111358/
https://ncbi.nlm.nih.gov/pubmed/27662872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-4035-6_8
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