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Super-Enhancers at the Nanog Locus Differentially Regulate Neighboring Pluripotency-Associated Genes

Super-enhancers are tissue specific cis-regulatory elements that drive expression of genes associated with cell identity and malignancy. A cardinal feature of super-enhancers is that they are transcribed to produce long non-coding RNAs (eRNAs). It remains unclear whether epigenetically indistinguish...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Blinka, Steven, Reimer, Michael H., Pulakanti, Kirthi, Rao, Sridhar
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5111363/
https://ncbi.nlm.nih.gov/pubmed/27681417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.09.002
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