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Nanog Expression in Embryonic Stem Cells – An Ideal Model System to Dissect Enhancer Function

Embryonic stem cells (ESCs) are derived from the preimplantation embryo and can differentiate into virtually any other cell type (termed pluripotency), which is governed by lineage specific transcriptions factors (TFs) binding to cis regulatory elements (CREs) to mediate changes in gene expression....

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Detalhes bibliográficos
Publicado no:Bioessays
Main Authors: Blinka, Steven, Rao, Sridhar
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5878941/
https://ncbi.nlm.nih.gov/pubmed/28977693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201700086
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