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Nanog Expression in Embryonic Stem Cells – An Ideal Model System to Dissect Enhancer Function

Embryonic stem cells (ESCs) are derived from the preimplantation embryo and can differentiate into virtually any other cell type (termed pluripotency), which is governed by lineage specific transcriptions factors (TFs) binding to cis regulatory elements (CREs) to mediate changes in gene expression....

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Bibliografiske detaljer
Udgivet i:Bioessays
Main Authors: Blinka, Steven, Rao, Sridhar
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5878941/
https://ncbi.nlm.nih.gov/pubmed/28977693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201700086
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