Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells

Enhancers are genetic elements that regulate spatiotemporal gene expression. Enhancer function requires transcription factor (TF) binding and correlates with histone modifications. However, the extent to which TF binding and histone modifications functionally define active enhancers remains unclear....

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Bibliografske podrobnosti
izdano v:Cell Stem Cell
Main Authors: Barakat, Tahsin Stefan, Halbritter, Florian, Zhang, Man, Rendeiro, André F., Perenthaler, Elena, Bock, Christoph, Chambers, Ian
Format: Artigo
Jezik:Inglês
Izdano: Cell Press 2018
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6084406/
https://ncbi.nlm.nih.gov/pubmed/30033119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2018.06.014
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