Selective influence of Sox2 on POU transcription factor binding in embryonic and neural stem cells

Embryonic stem cell (ESC) identity is orchestrated by co-operativity between the transcription factors (TFs) Sox2 and the class V POU-TF Oct4 at composite Sox/Oct motifs. Neural stem cells (NSCs) lack Oct4 but express Sox2 and class III POU-TFs Oct6, Brn1 and Brn2. This raises the question of how So...

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Publicat a:EMBO Rep
Autors principals: Mistri, Tapan Kumar, Devasia, Arun George, Chu, Lee Thean, Ng, Wei Ping, Halbritter, Florian, Colby, Douglas, Martynoga, Ben, Tomlinson, Simon R, Chambers, Ian, Robson, Paul, Wohland, Thorsten
Format: Artigo
Idioma:Inglês
Publicat: John Wiley & Sons, Ltd 2015
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4576985/
https://ncbi.nlm.nih.gov/pubmed/26265007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201540467
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