A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal

Embryonic stem (ES) cell self-renewal efficiency is determined by the Nanog protein level. However, the protein partners of Nanog that function to direct self-renewal are unclear. Here, we identify a Nanog interactome of over 130 proteins including transcription factors, chromatin modifying complexe...

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Autors principals: Gagliardi, Alessia, Mullin, Nicholas P, Ying Tan, Zi, Colby, Douglas, Kousa, Anastasia I, Halbritter, Florian, Weiss, Jason T, Felker, Anastasia, Bezstarosti, Karel, Favaro, Rebecca, Demmers, Jeroen, Nicolis, Silvia K, Tomlinson, Simon R, Poot, Raymond A, Chambers, Ian
Format: Artigo
Idioma:Inglês
Publicat: European Molecular Biology Organization 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3746198/
https://ncbi.nlm.nih.gov/pubmed/23892456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.161
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