Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells

Enhancers are genetic elements that regulate spatiotemporal gene expression. Enhancer function requires transcription factor (TF) binding and correlates with histone modifications. However, the extent to which TF binding and histone modifications functionally define active enhancers remains unclear....

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Publicat a:Cell Stem Cell
Autors principals: Barakat, Tahsin Stefan, Halbritter, Florian, Zhang, Man, Rendeiro, André F., Perenthaler, Elena, Bock, Christoph, Chambers, Ian
Format: Artigo
Idioma:Inglês
Publicat: Cell Press 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6084406/
https://ncbi.nlm.nih.gov/pubmed/30033119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2018.06.014
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