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Deletion of Tet proteins results in quantitative disparities during ESC differentiation partially attributable to alterations in gene expression
BACKGROUND: The Tet protein family (Tet1, Tet2, and Tet3) regulate DNA methylation through conversion of 5-methylcytosine to 5-hydroxymethylcytosine which can ultimately result in DNA demethylation and play a critical role during early mammalian development and pluripotency. While multiple groups ha...
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| Publicat a: | BMC Dev Biol |
|---|---|
| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6615237/ https://ncbi.nlm.nih.gov/pubmed/31286885 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12861-019-0196-6 |
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