The cohesin-associated protein Wapal is required for proper Polycomb-mediated gene silencing

BACKGROUND: The cohesin complex consists of multiple core subunits that play critical roles in mitosis and transcriptional regulation. The cohesin-associated protein Wapal plays a central role in off-loading cohesin to facilitate sister chromatid separation, but its role in regulating mammalian gene...

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Udgivet i:Epigenetics Chromatin
Main Authors: Stelloh, Cary, Reimer, Michael H., Pulakanti, Kirthi, Blinka, Steven, Peterson, Jonathan, Pinello, Luca, Jia, Shuang, Roumiantsev, Sergei, Hessner, Martin J., Milanovich, Samuel, Yuan, Guo-Cheng, Rao, Sridhar
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4832553/
https://ncbi.nlm.nih.gov/pubmed/27087855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-016-0063-7
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