NANOG reprograms prostate cancer cells to castration resistance via dynamically repressing and engaging the AR/FOXA1 signaling axis

The pluripotency transcription factor NANOG has been implicated in tumor development, and NANOG-expressing cancer cells manifest stem cell properties that sustain tumor homeostasis, mediate therapy resistance and fuel tumor progression. However, how NANOG converges on somatic circuitry to trigger on...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Cell Discov
Главные авторы: Jeter, Collene R, Liu, Bigang, Lu, Yue, Chao, Hsueh-Ping, Zhang, Dingxiao, Liu, Xin, Chen, Xin, Li, Qiuhui, Rycaj, Kiera, Calhoun-Davis, Tammy, Yan, Li, Hu, Qiang, Wang, Jianmin, Shen, Jianjun, Liu, Song, Tang, Dean G
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2016
Предметы:
Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5109294/
https://ncbi.nlm.nih.gov/pubmed/27867534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/celldisc.2016.41
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы