A pH‐ and ionic strength‐dependent conformational change in the neck region regulates DNGR‐1 function in dendritic cells

DNGR‐1 is receptor expressed by certain dendritic cell (DC) subsets and by DC precursors in mouse. It possesses a C‐type lectin‐like domain (CTLD) followed by a poorly characterized neck region coupled to a transmembrane region and short intracellular tail. The CTLD of DNGR‐1 binds F‐actin exposed b...

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Bibliografiska uppgifter
I publikationen:EMBO J
Huvudupphovsmän: Hanč, Pavel, Schulz, Oliver, Fischbach, Hanna, Martin, Stephen R, Kjær, Svend, Reis e Sousa, Caetano
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2016
Ämnen:
Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5109244/
https://ncbi.nlm.nih.gov/pubmed/27753620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201694695
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