Myosin II Synergizes with F-Actin to Promote DNGR-1-Dependent Cross-Presentation of Dead Cell-Associated Antigens

Conventional type 1 DCs (cDC1s) excel at cross-presentation of dead cell-associated antigens partly because they express DNGR-1, a receptor that recognizes exposed actin filaments on dead cells. In vitro polymerized F-actin can be used as a synthetic ligand for DNGR-1. However, cellular F-actin is d...

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Publicado en:Cell Rep
Autores principales: Schulz, Oliver, Hanč, Pavel, Böttcher, Jan P., Hoogeboom, Robbert, Diebold, Sandra S., Tolar, Pavel, Reis e Sousa, Caetano
Formato: Artigo
Lenguaje:Inglês
Publicado: Cell Press 2018
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6057488/
https://ncbi.nlm.nih.gov/pubmed/29996102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.06.038
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