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Cross-presentation of cell-associated antigens by CD8α(+) dendritic cells is attributable to their ability to internalize dead cells

In the mouse, cross-presentation is an exclusive property of the CD8α(+) subset of dendritic cells (DC) but the basis for this selectivity remains unclear. Here we report that splenic CD8α(+) DC are much superior to other DC subsets in internalizing dying cells in vitro. In contrast, CD8α(+), CD8α(−...

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Detalhes bibliográficos
Main Authors: Schulz, Oliver, e Sousa, Caetano Reis
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1782783/
https://ncbi.nlm.nih.gov/pubmed/12383197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.2002.01513.x
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