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Direct activation of antigen-presenting cells is required for CD8(+) T-cell priming and tumor vaccination
Successful priming of adaptive immune responses is crucially dependent on innate activation signals that convert resting antigen-presenting cells (APCs) into immunogenic ones. APCs expressing the relevant innate pattern recognition receptors can be directly activated by pathogen-associated molecular...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3198339/ https://ncbi.nlm.nih.gov/pubmed/21987815 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1108945108 |
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