Mucosal-Pull Induction of Lung-Resident Memory CD8 T Cells in Parenteral TB Vaccine-Primed Hosts Requires Cognate Antigens and CD4 T Cells

Tissue-resident memory T cells (T(RM)) are critical to host defense at mucosal tissue sites. However, the parenteral route of immunization as the most commonly used immunization route in practice is not effective in inducing mucosal T(RM) cells particularly in the lung. While various respiratory muc...

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Bibliographische Detailangaben
Veröffentlicht in:Front Immunol
Hauptverfasser: Haddadi, Siamak, Vaseghi-Shanjani, Maryam, Yao, Yushi, Afkhami, Sam, D'Agostino, Michael R., Zganiacz, Anna, Jeyanathan, Mangalakumari, Xing, Zhou
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2019
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6747041/
https://ncbi.nlm.nih.gov/pubmed/31552032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02075
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