Enhancement of Antituberculosis Immunity in a Humanized Model System by a Novel Virus-Vectored Respiratory Mucosal Vaccine

BACKGROUND. The translation of preclinically promising novel tuberculosis vaccines to ultimate human applications has been challenged by the lack of animal models with an immune system equivalent to the human immune system in its genetic diversity and level of susceptibility to tuberculosis. METHODS...

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Publicado no:J Infect Dis
Main Authors: Yao, Yushi, Lai, Rocky, Afkhami, Sam, Haddadi, Siamak, Zganiacz, Anna, Vahedi, Fatemeh, Ashkar, Ali A., Kaushic, Charu, Jeyanathan, Mangalakumari, Xing, Zhou
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
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Major Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5853534/
https://ncbi.nlm.nih.gov/pubmed/28531291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jix252
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