Enhancement of Antituberculosis Immunity in a Humanized Model System by a Novel Virus-Vectored Respiratory Mucosal Vaccine

BACKGROUND. The translation of preclinically promising novel tuberculosis vaccines to ultimate human applications has been challenged by the lack of animal models with an immune system equivalent to the human immune system in its genetic diversity and level of susceptibility to tuberculosis. METHODS...

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Publicado en:J Infect Dis
Autores principales: Yao, Yushi, Lai, Rocky, Afkhami, Sam, Haddadi, Siamak, Zganiacz, Anna, Vahedi, Fatemeh, Ashkar, Ali A., Kaushic, Charu, Jeyanathan, Mangalakumari, Xing, Zhou
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2017
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Major Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5853534/
https://ncbi.nlm.nih.gov/pubmed/28531291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jix252
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