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Direct activation of antigen-presenting cells is required for CD8(+) T-cell priming and tumor vaccination

Successful priming of adaptive immune responses is crucially dependent on innate activation signals that convert resting antigen-presenting cells (APCs) into immunogenic ones. APCs expressing the relevant innate pattern recognition receptors can be directly activated by pathogen-associated molecular...

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Bibliografiske detaljer
Main Authors: Kratky, Wolfgang, Reis e Sousa, Caetano, Oxenius, Annette, Spörri, Roman
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3198339/
https://ncbi.nlm.nih.gov/pubmed/21987815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1108945108
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