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A pH‐ and ionic strength‐dependent conformational change in the neck region regulates DNGR‐1 function in dendritic cells

DNGR‐1 is receptor expressed by certain dendritic cell (DC) subsets and by DC precursors in mouse. It possesses a C‐type lectin‐like domain (CTLD) followed by a poorly characterized neck region coupled to a transmembrane region and short intracellular tail. The CTLD of DNGR‐1 binds F‐actin exposed b...

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Dades bibliogràfiques
Publicat a:EMBO J
Autors principals: Hanč, Pavel, Schulz, Oliver, Fischbach, Hanna, Martin, Stephen R, Kjær, Svend, Reis e Sousa, Caetano
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5109244/
https://ncbi.nlm.nih.gov/pubmed/27753620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201694695
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