Use of ferrous iron by metallo-β-lactamases

Metallo-β-lactamases (MBLs) catalyse the hydrolysis of almost all β-lactam antibacterials including the latest generation carbapenems and are a growing worldwide clinical problem. It is proposed that MBLs employ one or two zinc ion cofactors in vivo. Isolated MBLs are reported to use transition meta...

Full description

Saved in:
Bibliographic Details
Published in:J Inorg Biochem
Main Authors: Cahill, Samuel T., Tarhonskaya, Hanna, Rydzik, Anna M., Flashman, Emily, McDonough, Michael A., Schofield, Christopher J., Brem, Jürgen
Format: Artigo
Language:Inglês
Published: Elsevier 2016
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5108564/
https://ncbi.nlm.nih.gov/pubmed/27498591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jinorgbio.2016.07.013
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items