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The sensitivity of the DNA damage checkpoint prevents oocyte maturation in endometriosis
Mouse oocytes respond to DNA damage by arresting in meiosis I through activity of the Spindle Assembly Checkpoint (SAC) and DNA Damage Response (DDR) pathways. It is currently not known if DNA damage is the primary trigger for arrest, or if the pathway is sensitive to levels of DNA damage experience...
Gardado en:
| Publicado en: | Sci Rep |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5107963/ https://ncbi.nlm.nih.gov/pubmed/27841311 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep36994 |
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