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Pharmacological Inhibition of the DNA Damage Checkpoint Prevents Radiation-Induced Oocyte Death

Ovarian function is directly correlated with survival of the primordial follicle reserve. Women diagnosed with cancer have a primary imperative of treating the cancer, but since the resting oocytes are hypersensitive to the DNA-damaging modalities of certain chemo- and radiotherapeutic regimens, suc...

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Detalhes bibliográficos
Publicado no:Genetics
Main Authors: Rinaldi, Vera D., Hsieh, Kristin, Munroe, Robert, Bolcun-Filas, Ewelina, Schimenti, John C.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5560790/
https://ncbi.nlm.nih.gov/pubmed/28576861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.117.203455
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