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Genetic Evidence That Synaptonemal Complex Axial Elements Govern Recombination Pathway Choice in Mice

Chiasmata resulting from interhomolog recombination are critical for proper chromosome segregation at meiotic metaphase I, thus preventing aneuploidy and consequent deleterious effects. Recombination in meiosis is driven by programmed induction of double strand breaks (DSBs), and the repair of these...

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Библиографические подробности
Главные авторы: Li, Xin Chenglin, Bolcun-Filas, Ewelina, Schimenti, John C.
Формат: Artigo
Язык:Inglês
Опубликовано: Genetics Society of America 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3176111/
https://ncbi.nlm.nih.gov/pubmed/21750255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.111.130674
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