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Genetic Evidence That Synaptonemal Complex Axial Elements Govern Recombination Pathway Choice in Mice

Chiasmata resulting from interhomolog recombination are critical for proper chromosome segregation at meiotic metaphase I, thus preventing aneuploidy and consequent deleterious effects. Recombination in meiosis is driven by programmed induction of double strand breaks (DSBs), and the repair of these...

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Détails bibliographiques
Auteurs principaux: Li, Xin Chenglin, Bolcun-Filas, Ewelina, Schimenti, John C.
Format: Artigo
Langue:Inglês
Publié: Genetics Society of America 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3176111/
https://ncbi.nlm.nih.gov/pubmed/21750255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.111.130674
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