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The sensitivity of the DNA damage checkpoint prevents oocyte maturation in endometriosis
Mouse oocytes respond to DNA damage by arresting in meiosis I through activity of the Spindle Assembly Checkpoint (SAC) and DNA Damage Response (DDR) pathways. It is currently not known if DNA damage is the primary trigger for arrest, or if the pathway is sensitive to levels of DNA damage experience...
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Publicado no: | Sci Rep |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5107963/ https://ncbi.nlm.nih.gov/pubmed/27841311 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep36994 |
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