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DNA damage response during mouse oocyte maturation

Because low levels of DNA double strand breaks (DSBs) appear not to activate the ATM-mediated prophase I checkpoint in full-grown oocytes, there may exist mechanisms to protect chromosome integrity during meiotic maturation. Using live imaging we demonstrate that low levels of DSBs induced by the ra...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Mayer, Alexandra, Baran, Vladimir, Sakakibara, Yogo, Brzakova, Adela, Ferencova, Ivana, Motlik, Jan, Kitajima, Tomoya S., Schultz, Richard M., Solc, Petr
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5056612/
https://ncbi.nlm.nih.gov/pubmed/26745237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1128592
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