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Aurora Kinase A Drives MTOC Biogenesis but Does Not Trigger Resumption of Meiosis in Mouse Oocytes Matured In Vivo

Aurora kinase A (AURKA) is an important mitotic kinase involved in the G2/M transition, centrosome maturation and separation, and spindle formation in somatic cells. We used transgenic models that specifically overexpress in mouse oocytes either wild-type (WT-AURKA) or a catalytically inactive (kina...

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מידע ביבליוגרפי
Main Authors: Solc, Petr, Baran, Vladimir, Mayer, Alexandra, Bohmova, Tereza, Panenkova-Havlova, Gabriela, Saskova, Adela, Schultz, Richard M., Motlik, Jan
פורמט: Artigo
שפה:Inglês
יצא לאור: Society for the Study of Reproduction, Inc. 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3507544/
https://ncbi.nlm.nih.gov/pubmed/22837479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.112.101014
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