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Analysis of inflammation-induced depression of home cage wheel running in rats reveals the difference between opioid antinociception and restoration of function

Opioids are effective at inhibiting responses to noxious stimuli in rodents, but have limited efficacy and many side effects in chronic pain patients. One reason for this disconnect is that nociception is typically assessed using withdrawal from noxious stimuli in animals, whereas chronic pain patie...

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Библиографические подробности
Опубликовано в: :Behav Brain Res
Главные авторы: Kandasamy, Ram, Calsbeek, Jonas J., Morgan, Michael M.
Формат: Artigo
Язык:Inglês
Опубликовано: 2016
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5107346/
https://ncbi.nlm.nih.gov/pubmed/27746208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbr.2016.10.024
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