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Analysis of inflammation-induced depression of home cage wheel running in rats reveals the difference between opioid antinociception and restoration of function

Opioids are effective at inhibiting responses to noxious stimuli in rodents, but have limited efficacy and many side effects in chronic pain patients. One reason for this disconnect is that nociception is typically assessed using withdrawal from noxious stimuli in animals, whereas chronic pain patie...

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Detalhes bibliográficos
Publicado no:Behav Brain Res
Main Authors: Kandasamy, Ram, Calsbeek, Jonas J., Morgan, Michael M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5107346/
https://ncbi.nlm.nih.gov/pubmed/27746208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbr.2016.10.024
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