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Use of home cage wheel running to assess the behavioural effects of administering a mu/delta opioid receptor heterodimer antagonist for spontaneous morphine withdrawal in the rat

Opioid abuse is a major health problem. The objective of the present study was to evaluate the potentially disruptive side effects and therapeutic potential of a novel antagonist (D24M) of the mu-/delta-opioid receptor (MOR/DOR) heterodimer in male rats. Administration of high doses of D24M (1 &...

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Detalhes bibliográficos
Publicado no:Behav Brain Res
Main Authors: Morgan, Michael M., Peecher, Danielle L., Streicher, John M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7655591/
https://ncbi.nlm.nih.gov/pubmed/33031872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbr.2020.112953
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