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Home cage wheel running is an objective and clinically relevant method to assess inflammatory pain in male and female rats

BACKGROUND: The assessment of nociception in preclinical studies is undergoing a transformation from pain-evoked to pain-depressed tests to more closely mimic the effects of clinical pain. Many inflammatory pain-depressed behaviors (reward seeking, locomotion) have been examined, but these tests are...

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Detalhes bibliográficos
Publicado no:J Neurosci Methods
Main Authors: Kandasamy, Ram, Calsbeek, Jonas J., Morgan, Michael M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4801754/
https://ncbi.nlm.nih.gov/pubmed/26891874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneumeth.2016.02.013
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