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Home cage wheel running is an objective and clinically relevant method to assess inflammatory pain in male and female rats
BACKGROUND: The assessment of nociception in preclinical studies is undergoing a transformation from pain-evoked to pain-depressed tests to more closely mimic the effects of clinical pain. Many inflammatory pain-depressed behaviors (reward seeking, locomotion) have been examined, but these tests are...
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Publicado no: | J Neurosci Methods |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4801754/ https://ncbi.nlm.nih.gov/pubmed/26891874 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneumeth.2016.02.013 |
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