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Exosome-mediated Transfer of α(v)β(3) Integrin from Tumorigenic to Non-Tumorigenic Cells Promotes a Migratory Phenotype

The α(v)β(3) integrin is known to be highly up-regulated during cancer progression and promotes a migratory and metastatic phenotype in many types of tumors. We hypothesized that the α(v)β(3) integrin is transferred through exosomes and, upon transfer, has the ability to support functional aberratio...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Mol Cancer Res
Päätekijät: Singh, Amrita, Fedele, Carmine, Lu, Huimin, Nevalainen, Marja T., Keen, James H., Languino, Lucia R.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5107121/
https://ncbi.nlm.nih.gov/pubmed/27439335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-16-0058
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