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IGF-IR Promotes Prostate Cancer Growth by Stabilizing α(5)β(1) Integrin Protein Levels

Dynamic crosstalk between growth factor receptors, cell adhesion molecules and extracellular matrix is essential for cancer cell migration and invasion. Integrins are transmembrane receptors that bind extracellular matrix proteins and enable cell adhesion and cytoskeletal organization. They also med...

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Autors principals: Sayeed, Aejaz, Fedele, Carmine, Trerotola, Marco, Ganguly, Kirat K., Languino, Lucia R.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3793919/
https://ncbi.nlm.nih.gov/pubmed/24130778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0076513
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