IGF-IR Promotes Prostate Cancer Growth by Stabilizing α(5)β(1) Integrin Protein Levels

Dynamic crosstalk between growth factor receptors, cell adhesion molecules and extracellular matrix is essential for cancer cell migration and invasion. Integrins are transmembrane receptors that bind extracellular matrix proteins and enable cell adhesion and cytoskeletal organization. They also med...

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Bibliographic Details
Main Authors: Sayeed, Aejaz, Fedele, Carmine, Trerotola, Marco, Ganguly, Kirat K., Languino, Lucia R.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3793919/
https://ncbi.nlm.nih.gov/pubmed/24130778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0076513
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