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IGF-IR Promotes Prostate Cancer Growth by Stabilizing α(5)β(1) Integrin Protein Levels

Dynamic crosstalk between growth factor receptors, cell adhesion molecules and extracellular matrix is essential for cancer cell migration and invasion. Integrins are transmembrane receptors that bind extracellular matrix proteins and enable cell adhesion and cytoskeletal organization. They also med...

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Detalhes bibliográficos
Main Authors: Sayeed, Aejaz, Fedele, Carmine, Trerotola, Marco, Ganguly, Kirat K., Languino, Lucia R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3793919/
https://ncbi.nlm.nih.gov/pubmed/24130778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0076513
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