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Trop-2 promotes prostate cancer metastasis by modulating β(1) integrin functions

The molecular mechanisms underlying metastatic dissemination are still not completely understood. We have recently shown that β(1) integrin-dependent cell adhesion to fibronectin (FN) and signaling are affected by a transmembrane molecule, Trop-2, which is frequently upregulated in human carcinomas....

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Detalhes bibliográficos
Main Authors: Trerotola, Marco, Jernigan, Danielle L., Liu, Qin, Siddiqui, Javed, Fatatis, Alessandro, Languino, Lucia R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3655712/
https://ncbi.nlm.nih.gov/pubmed/23536555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-3266
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