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α(v)β(6) Integrin Is Required for TGFβ1-Mediated Matrix Metalloproteinase2 Expression
TGFβ1 activity depends on a complex signaling cascade that controls expression of several genes. Among others, TGFβ1 regulates expression of matrix metalloproteinases (MMPs) through activation of Smads. Here, we demonstrate for the first time that the α(v)β(6) integrin interacts with TGFβ receptor I...
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| Pubblicato in: | Biochem J |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4363118/ https://ncbi.nlm.nih.gov/pubmed/25558779 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20140698 |
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