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Microenvironment-dependent growth of pre-neoplastic and malignant plasma cells in humanized mice
Most human cancers including myeloma are preceded by a precursor state. There is an unmet need for in vivo models to study the interaction of human preneoplastic cells in the bone marrow microenvironment with non-malignant cells. Here, we genetically humanized mice to permit the growth of primary hu...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Nat Med |
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| Κύριοι συγγραφείς: | , , , , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2016
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5101153/ https://ncbi.nlm.nih.gov/pubmed/27723723 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.4202 |
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