Dendritic cell–mediated activation-induced cytidine deaminase (AID)–dependent induction of genomic instability in human myeloma

Tumor microenvironment (TME) is commonly implicated in regulating the growth of tumors, but whether it can directly alter the genetics of tumors is not known. Genomic instability and dendritic cell (DC) infiltration are common features of several cancers, including multiple myeloma (MM). Mechanisms...

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Detalhes bibliográficos
Main Authors: Koduru, Srinivas, Wong, Ellice, Strowig, Till, Sundaram, Ranjini, Zhang, Lin, Strout, Matthew P., Flavell, Richard A., Schatz, David G., Dhodapkar, Kavita M., Dhodapkar, Madhav V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2012
Assuntos:
Lymphoid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3311257/
https://ncbi.nlm.nih.gov/pubmed/22234692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-08-376236
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