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Microenvironment-dependent growth of pre-neoplastic and malignant plasma cells in humanized mice
Most human cancers including myeloma are preceded by a precursor state. There is an unmet need for in vivo models to study the interaction of human preneoplastic cells in the bone marrow microenvironment with non-malignant cells. Here, we genetically humanized mice to permit the growth of primary hu...
Kaydedildi:
Yayımlandı: | Nat Med |
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Asıl Yazarlar: | , , , , , , , , , , , , , |
Materyal Türü: | Artigo |
Dil: | Inglês |
Baskı/Yayın Bilgisi: |
2016
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Konular: | |
Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5101153/ https://ncbi.nlm.nih.gov/pubmed/27723723 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.4202 |
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