Transcriptome Profiling in Rat Inbred Strains and Experimental Cross Reveals Discrepant Genetic Architecture of Genome-Wide Gene Expression

To test the impact of genetic heterogeneity on cis- and trans-mediated mechanisms of gene expression regulation, we profiled the transcriptome of adipose tissue in 20 inbred congenic strains derived from diabetic Goto–Kakizaki (GK) rats and Brown–Norway (BN) controls, which contain well-defined bloc...

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Dades bibliogràfiques
Publicat a:G3 (Bethesda)
Autors principals: Kaisaki, Pamela J., Otto, Georg W., Argoud, Karène, Collins, Stephan C., Wallis, Robert H., Wilder, Steven P., Yau, Anthony C. Y., Hue, Christophe, Calderari, Sophie, Bihoreau, Marie-Thérèse, Cazier, Jean-Baptiste, Mott, Richard, Gauguier, Dominique
Format: Artigo
Idioma:Inglês
Publicat: Genetics Society of America 2016
Matèries:
Investigations
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5100866/
https://ncbi.nlm.nih.gov/pubmed/27646706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.116.033274
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