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Conserved properties of genetic architecture of renal and fat transcriptomes in rat models of insulin resistance

To define renal molecular mechanisms that are affected by permanent hyperglycaemia and might promote phenotypes relevant to diabetic nephropathy, we carried out linkage analysis of genome-wide gene transcription in the kidneys of F2 offspring from the Goto-Kakizaki (GK) rat model of type 2 diabetes...

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Publicat a:Dis Model Mech
Autors principals: Otto, Georg W., Kaisaki, Pamela J., Brial, Francois, Le Lay, Aurélie, Cazier, Jean-Baptiste, Mott, Richard, Gauguier, Dominique
Format: Artigo
Idioma:Inglês
Publicat: The Company of Biologists Ltd 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6679378/
https://ncbi.nlm.nih.gov/pubmed/31213483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.038539
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