Systems Genetics of Hepatic Metabolome Reveals Octopamine as a Target for Non-Alcoholic Fatty Liver Disease Treatment

Non-alcoholic fatty liver disease (NAFLD) is often associated with obesity and type 2 diabetes. To disentangle etiological relationships between these conditions and identify genetically-determined metabolites involved in NAFLD processes, we mapped (1)H nuclear magnetic resonance (NMR) metabolomic a...

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Udgivet i:Sci Rep
Main Authors: Brial, Francois, Le Lay, Aurélie, Hedjazi, Lyamine, Tsang, Tsz, Fearnside, Jane F., Otto, Georg W., Alzaid, Fawaz, Wilder, Steven P., Venteclef, Nicolas, Cazier, Jean-Baptiste, Nicholson, Jeremy K., Day, Chris, Burt, Alastair D., Gut, Ivo G., Lathrop, Mark, Dumas, Marc-Emmanuel, Gauguier, Dominique
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6403227/
https://ncbi.nlm.nih.gov/pubmed/30842494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-40153-0
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