Transcriptome Profiling in Rat Inbred Strains and Experimental Cross Reveals Discrepant Genetic Architecture of Genome-Wide Gene Expression

To test the impact of genetic heterogeneity on cis- and trans-mediated mechanisms of gene expression regulation, we profiled the transcriptome of adipose tissue in 20 inbred congenic strains derived from diabetic Goto–Kakizaki (GK) rats and Brown–Norway (BN) controls, which contain well-defined bloc...

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Foilsithe in:G3 (Bethesda)
Main Authors: Kaisaki, Pamela J., Otto, Georg W., Argoud, Karène, Collins, Stephan C., Wallis, Robert H., Wilder, Steven P., Yau, Anthony C. Y., Hue, Christophe, Calderari, Sophie, Bihoreau, Marie-Thérèse, Cazier, Jean-Baptiste, Mott, Richard, Gauguier, Dominique
Formáid: Artigo
Teanga:Inglês
Foilsithe: Genetics Society of America 2016
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Investigations
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5100866/
https://ncbi.nlm.nih.gov/pubmed/27646706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.116.033274
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