High-resolution structure of the presynaptic RAD51 filament on single-stranded DNA by electron cryo-microscopy

Homologous DNA recombination (HR) by the RAD51 recombinase enables error-free DNA break repair. To execute HR, RAD51 first forms a presynaptic filament on single-stranded (ss) DNA, which catalyses pairing with homologous double-stranded (ds) DNA. Here, we report a structure for the presynaptic human...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Autores principales: Short, Judith M., Liu, Yang, Chen, Shaoxia, Soni, Neelesh, Madhusudhan, Mallur S., Shivji, Mahmud K.K., Venkitaraman, Ashok R.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2016
Materias:
NAR Breakthrough Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5100573/
https://ncbi.nlm.nih.gov/pubmed/27596592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw783
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares