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Elimination of unaltered DNA in mixed clinical samples via nuclease-assisted minor-allele enrichment

Presence of excess unaltered, wild-type (WT) DNA providing no information of biological or clinical value often masks rare alterations containing diagnostic or therapeutic clues in cancer, prenatal diagnosis, infectious diseases or organ transplantation. With the surge of high-throughput technologie...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nucleic Acids Res
Egile Nagusiak: Song, Chen, Liu, Yibin, Fontana, Rachel, Makrigiorgos, Alexander, Mamon, Harvey, Kulke, Matthew H., Makrigiorgos, G. Mike
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5100565/
https://ncbi.nlm.nih.gov/pubmed/27431322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw650
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